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Showing 1 to 12 of 154 entries
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Weekly cisplatin may reverse liver dysfunction and jaundice caused by diffuse liver metastases of solid tumors.

Hepatic medicine : evidence and research

Gabrovska M, Geurs F, Ponette S, Ponette J, Bulte K, Derveaux L, Kempeneers I.
PMID: 24623997
Hepat Med. 2009 Oct 30;1:9-12. doi: 10.2147/hmer.s7574. eCollection 2009.

Few data are available on patient management in jaundice caused by liver metastases of solid tumors (nonbreast and noncolon origin). We report the first patient series consecutively treated with cisplatin weekly in patients with severe jaundice and liver failure...

Should NS5A inhibitors serve as the scaffold for all-oral anti-HCV combination therapies?.

Hepatic medicine : evidence and research

Janardhan SV, Reau NS.
PMID: 25926761
Hepat Med. 2015 Apr 16;7:11-20. doi: 10.2147/HMER.S79584. eCollection 2015.

Chronic hepatitis C virus (HCV) infection represents a global health problem that affects up to 130-150 million people worldwide. The HCV treatment landscape has been transformed recently by the introduction of direct-acting antiviral (DAA) agents that target viral proteins,...

Tyrosine levels are associated with insulin resistance in patients with nonalcoholic fatty liver disease.

Hepatic medicine : evidence and research

Kawanaka M, Nishino K, Oka T, Urata N, Nakamura J, Suehiro M, Kawamoto H, Chiba Y, Yamada G.
PMID: 26082668
Hepat Med. 2015 Jun 03;7:29-35. doi: 10.2147/HMER.S79100. eCollection 2015.

OBJECTIVE: Amino acid imbalance is often found in patients with cirrhosis, and this imbalance is associated with insulin resistance. However, the mechanism underlying the relationship between amino acid imbalance and insulin resistance remains unclear. We evaluated serum amino acid...

Hepatitis C in Argentina: epidemiology and treatment.

Hepatic medicine : evidence and research

Gaite LA, Marciano S, Galdame OA, Gadano AC.
PMID: 24966701
Hepat Med. 2014 May 27;6:35-43. doi: 10.2147/HMER.S57774. eCollection 2014.

Hepatitis C is the leading cause of chronic hepatitis, cirrhosis, and liver cancer in Argentina, where from 1.5% to 2.5% of adults are infected. Most of the infections were acquired 30-50 years ago. It is estimated that more than...

Transmission, diagnosis, and management of hepatitis E: an update.

Hepatic medicine : evidence and research

Mirazo S, Ramos N, Mainardi V, Gerona S, Arbiza J.
PMID: 24966702
Hepat Med. 2014 Jun 03;6:45-59. doi: 10.2147/HMER.S63417. eCollection 2014.

Hepatitis E virus (HEV) infection is an important public health concern in many developing countries, causing waterborne outbreaks as well as sporadic autochthonous hepatitis. HEV is mainly transmitted by the fecal-oral route in endemic areas through drinking of contaminated...

Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response.

Hepatic medicine : evidence and research

Dash S, Chava S, Chandra PK, Aydin Y, Balart LA, Wu T.
PMID: 26955295
Hepat Med. 2016 Feb 22;8:9-20. doi: 10.2147/HMER.S63700. eCollection 2016.

Autophagy is an intracellular lysosomal degradation process performed by the cells to maintain energy balance. The autophagy response plays an important role in the progression of liver disease due to hepatitis virus infection, alcoholic liver disease, nonalcoholic fatty liver...

Challenging hepatitis C-infected liver transplant patients.

Hepatic medicine : evidence and research

Oliver M, Ortiz CC, Ortiz J.
PMID: 26889091
Hepat Med. 2016 Jan 18;8:1-8. doi: 10.2147/HMER.S96110. eCollection 2016.

Caring for liver transplant patients suffering from chronic hepatitis C virus (HCV) infection is a challenging task for transplant surgeons and primary physicians alike. HCV is the leading cause of liver transplantation in the USA and comes with a...

Overt hepatic encephalopathy in Italy: clinical outcomes and healthcare costs.

Hepatic medicine : evidence and research

Roggeri DP, Roggeri A, Rossi E, Cinconze E, Gasbarrini A, Monici Preti P, De Rosa M.
PMID: 26203290
Hepat Med. 2015 Jul 13;7:37-42. doi: 10.2147/HMER.S87594. eCollection 2015.

PURPOSE: Hepatic encephalopathy (HE) is a recurrent severe complication of progressive hepatic cirrhosis. The aim of this study is to evaluate the average annual direct healthcare costs for the treatment of patients with overt HE in Italy.PATIENTS AND METHODS:...

Metabolic syndrome in chronic hepatitis C infection: does it still matter in the era of directly acting antiviral therapy?.

Hepatic medicine : evidence and research

Lim T.
PMID: 25506251
Hepat Med. 2014 Dec 03;6:113-8. doi: 10.2147/HMER.S60083. eCollection 2014.

Metabolic syndrome is prevalent in patients with hepatitis C virus (HCV) infection. Given the pandemic spread of HCV infection and metabolic syndrome, the burden of their interaction is a major public health issue. The presence of metabolic syndrome accelerates...

Hepatitis C in the Russian Federation: challenges and future directions.

Hepatic medicine : evidence and research

Mukomolov S, Trifonova G, Levakova I, Bolsun D, Krivanogova E.
PMID: 27217802
Hepat Med. 2016 May 05;8:51-60. doi: 10.2147/HMER.S50172. eCollection 2016.

Hepatitis C virus (HCV) infection is one of the most prevalent health problems in the world. Official registration of HCV infections in the Russian Federation started in 1994. Two clinical forms of infection - acute and chronic hepatitis C...

Autonomic dysfunction in chronic liver disease.

Hepatic medicine : evidence and research

Frith J, Newton JL.
PMID: 24367224
Hepat Med. 2011 Aug 23;3:81-7. doi: 10.2147/HMER.S16312.

It is becoming increasingly clear that quality of life (QOL) is impaired in those with chronic liver disease (CLD). One of the most important contributors to impaired QOL is the symptomatic burden which can range from slight to debilitating....

Update on new approaches in the management of hepatocellular carcinoma.

Hepatic medicine : evidence and research

Cabibbo G, Antonucci M, Genco C.
PMID: 24367214
Hepat Med. 2010 Nov 26;2:163-73. doi: 10.2147/HMER.S7132.

Hepatocellular carcinoma (HCC) is a major health problem. It is currently the third cause of cancer-related death, it is highly prevalent in the Asia-Pacific region and Africa, and is increasing in Western countries. The natural history of HCC is...

Showing 1 to 12 of 154 entries